Asked in ETEA MDCAT 2018 2018Moderate

Which of the following is not part of the first line of defense?

Correct answer: C. Interferon

  • A. Sebum
  • B. Perspiration
  • C. Interferon
  • D. Epidermis

Explanation

The first line of defense includes physical and chemical barriers like the skin (including the epidermis), sebum, and perspiration, which help prevent pathogens from entering the body. Sebum and perspiration are secretions that support these barriers. Interferon, however, is part of the second line of defense. It is a protein that aids in the immune response by inhibiting viral replication and activating immune cells. This distinction makes interferon not a component of the first line of defense.

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About Specific Defense Mechanism

Specific defense mechanisms provide targeted immunity through B lymphocytes, T lymphocytes, antibodies and memory cells that recognize particular antigens. Questions cover humoral and cell mediated responses, clonal selection, primary and secondary immune responses, vaccination and passive immunity, while distinguishing adaptive defenses from the immediate, non specific innate response.

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