Which immune reaction is primarily mediated by IgE and mast-cell degranulation?
Correct answer: A. Type I hypersensitivity
- A. Type I hypersensitivity
- B. Type II hypersensitivity
- C. Type III hypersensitivity
- D. Type IV hypersensitivity
Explanation
Type I hypersensitivity is an immediate allergic reaction involving IgE bound to mast cells, followed by mediator release after re-exposure to the antigen. Type IV hypersensitivity is delayed and is mainly mediated by T cells rather than IgE.
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About Veterinary Microbiology and Immunology
Covers the structure, classification, growth and transmission of bacteria, viruses, fungi and other disease causing microorganisms in animals. It explains innate and acquired immunity, antibodies, antigens, vaccination, hypersensitivity and diagnostic methods, while distinguishing infectious agents from the immune responses they produce.
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