Which drug is not acetylated ?
Correct answer: A. Metaclopramide
- A. Metaclopramide
- B. INH
- C. Dapsone
- D. Hydralazine
Explanation
Metoclopramide is not a clinically important acetylation substrate, whereas isoniazid, dapsone and hydralazine undergo acetylation with genetically variable rates. This is the basis of the rapid and slow acetylator distinction.
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