Which drug is not acetylated ?

Correct answer: A. Metaclopramide

  • A. Metaclopramide
  • B. INH
  • C. Dapsone
  • D. Hydralazine

Explanation

Metoclopramide is not a clinically important acetylation substrate, whereas isoniazid, dapsone and hydralazine undergo acetylation with genetically variable rates. This is the basis of the rapid and slow acetylator distinction.

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