Which component of bacterial endotoxin is mainly responsible for its toxic effects?
Correct answer: B. Lipid A
- A. O antigen
- B. Lipid A
- C. Core polysaccharide
- D. Capsular polysaccharide
Explanation
Lipid A is the toxic portion of lipopolysaccharide in the outer membrane of Gram-negative bacteria. The O antigen mainly contributes to serological variation and is not the principal toxic component.
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Covers the structure, classification, growth and transmission of bacteria, viruses, fungi and other disease causing microorganisms in animals. It explains innate and acquired immunity, antibodies, antigens, vaccination, hypersensitivity and diagnostic methods, while distinguishing infectious agents from the immune responses they produce.
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