Which cellular change is most characteristic of atrophy?
Correct answer: A. Reduced cell size and functional activity
- A. Reduced cell size and functional activity
- B. Increased cell size and protein synthesis
- C. Increased cell number from mitosis
- D. Replacement by a different mature cell type
Explanation
Atrophy involves a reduction in cell size and often a corresponding decrease in organ function. Increased cell size indicates hypertrophy, increased cell number indicates hyperplasia, and replacement by another cell type indicates metaplasia.
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Covers the causes and mechanisms of disease, cellular injury, inflammation, healing, circulatory disturbances, neoplasia and disorders of major organs. It also includes gross and microscopic pathological changes, specimen interpretation and the distinction between aetiology, pathogenesis, clinical signs and lesions.
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