Which among the following is a cell cycle specific anti-neoplastic drug ?
Correct answer: C. Methotrexate
- A. Cyclophosphamide
- B. Doxorubicin
- C. Methotrexate
- D. Cisplatin
Explanation
Methotrexate is cell-cycle specific because it inhibits dihydrofolate reductase during the S phase, blocking DNA synthesis. Cyclophosphamide, doxorubicin and cisplatin are generally classified as cell-cycle nonspecific agents.
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