Which adverse effect is most associated with long-term treatment with an atypical antipsychotic such as olanzapine?
Correct answer: B. Weight gain and raised blood glucose
- A. Severe hypoglycaemia
- B. Weight gain and raised blood glucose
- C. Permanent hearing loss
- D. Markedly reduced appetite
Explanation
Atypical antipsychotics may cause weight gain, dyslipidaemia and hyperglycaemia, so weight and metabolic findings need monitoring. Hypoglycaemia, hearing loss and reduced appetite are not the characteristic long-term concerns.
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About Analgesics and CNS Drugs
This area covers opioid and non-opioid analgesics, local anaesthetics, sedatives, anxiolytics, antidepressants, antipsychotics, antiepileptics and drugs for Parkinsonism. It examines therapeutic actions, dependence, respiratory depression, extrapyramidal effects, serotonin related toxicity and the distinction between pain relief, sedation and loss of consciousness.
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