Which action explains how furosemide produces its diuretic effect?
Correct answer: A. Blocks sodium reabsorption in the loop of Henle
- A. Blocks sodium reabsorption in the loop of Henle
- B. Increases sodium reabsorption in the collecting duct
- C. Blocks aldosterone receptors in the distal tubule
- D. Reduces filtration by constricting the renal artery
Explanation
Furosemide inhibits the sodium-potassium-chloride cotransporter in the thick ascending loop of Henle, causing marked sodium and water loss. Aldosterone blockade describes spironolactone, not furosemide.
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About Cardiovascular and Respiratory Drugs
Cardiovascular and respiratory drugs include antihypertensives, diuretics, antianginal agents, antiarrhythmics, cardiac glycosides, anticoagulants, bronchodilators, corticosteroids and cough medicines. Questions focus on mechanisms, indications, contraindications, toxicity and monitoring, especially the difference between drugs that reduce blood pressure, improve cardiac output or open narrowed airways.
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