Which action best describes the antiplatelet effect of low-dose aspirin?

Correct answer: A. Irreversibly inhibits platelet cyclooxygenase

  • A. Irreversibly inhibits platelet cyclooxygenase
  • B. Directly dissolves an established blood clot
  • C. Replaces clotting factors consumed during bleeding
  • D. Prevents fibrin breakdown in a damaged vessel

Explanation

Aspirin irreversibly inhibits platelet cyclooxygenase, reducing thromboxane A2 and platelet aggregation for the life of the platelet. It prevents new platelet-rich clots but does not directly dissolve an established clot.

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About Cardiovascular and Respiratory Drugs

Cardiovascular and respiratory drugs include antihypertensives, diuretics, antianginal agents, antiarrhythmics, cardiac glycosides, anticoagulants, bronchodilators, corticosteroids and cough medicines. Questions focus on mechanisms, indications, contraindications, toxicity and monitoring, especially the difference between drugs that reduce blood pressure, improve cardiac output or open narrowed airways.

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