Which action explains how calcitonin helps a patient with hypercalcaemia?
Correct answer: A. It inhibits osteoclast activity and lowers release of calcium from bone
- A. It inhibits osteoclast activity and lowers release of calcium from bone
- B. It increases intestinal calcium absorption and raises serum calcium
- C. It replaces parathyroid hormone and increases bone breakdown
- D. It prevents renal excretion of calcium and retains it in blood
Explanation
Calcitonin lowers serum calcium mainly by inhibiting osteoclast-mediated bone resorption and increasing renal calcium excretion. Vitamin D and parathyroid hormone have effects that generally increase calcium availability.
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About Endocrine and Diabetes Drugs
Endocrine pharmacology includes insulin preparations, oral antidiabetic drugs, thyroid and antithyroid medicines, corticosteroids, sex hormones and drugs affecting calcium balance. Questions address onset and duration, administration, monitoring, hypoglycaemia, steroid adverse effects and the difference between replacing a deficient hormone and suppressing excessive hormone activity.
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