When a glycoprotein is being synthesized for secretion from a cell, which route is it most likely to take?
Correct answer: C. Rough endoplasmic reticulum→ Smooth endoplasmic reticulum→ Golgi apparatus
- A. Golgi apparatus→ Rough endoplasmic reticulum→ Smooth endoplasmic reticulum
- B. Rough endoplasmic reticulum→ Golgi apparatus→ Smooth endoplasmic reticulum
- C. Rough endoplasmic reticulum→ Smooth endoplasmic reticulum→ Golgi apparatus
- D. Smooth endoplasmic reticulum→ Rough endoplasmic reticulum→ Golgi apparatus
Explanation
For the secretion of glyoprotein from the cell, protein is first synthesized by the ribosomes on RER. This protein then travel through RER to SER to be transferred to the Golgi apparatus through transport vesicles. On reaching the Golgi apparatus, this protein is modified into glycoprotein and then budded off from Golgi apparatus as goldi vesicles. These vesicles are then secreted out of the cell.
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