What is the advantage of sublingual route of administration of drugs_____________?
Correct answer: A. prevents or bypasses first pass effects
- A. prevents or bypasses first pass effects
- B. Easy to administer
- C. Lipid soluble
- D. Can be spitted out with signs of toxicity
Explanation
Sublingual absorption drains directly into the systemic circulation, largely bypassing hepatic first-pass metabolism and allowing a rapid effect. This route is particularly useful for drugs such as nitroglycerin that are extensively destroyed during first passage through the liver.
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