Asked in PMC Practice Test 18 (2021) 2021Moderate

What does an icosahedral capsid consist of?

Correct answer: D. Both options A and B are correct

  • A. Hexagonal capsomeres
  • B. Pentagonal capsomeres
  • C. Triangular Capsomeres
  • D. Both options A and B are correct

Explanation

Capsid: The coat is the outer covering of a viral particle which consists of a capsid and envelope. The capsid is the protective coat of protein surrounding the core. Capsid is composed of identical repeating subunits called capsomers (capsomeres). The number of capsomers is specific to a particular kind of virus. Icosahedral capsid: When the capsomers are arranged in 20 triangles, it is called icosahedral (polyhedral or spherical). In a bacteriophage capsid, there are 12 vertices and 20 faces. Two types of capsomeres constitute the icosahedral capsid: Pentagonal (pentons) at the vertices Hexagonal (hexons) at the faces. There are always twelve pentons, but the number of hexons varies among virus groups.

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About Viruses

Viruses are acellular infectious particles made of genetic material enclosed by a protein capsid, sometimes with a lipid envelope. Their replication depends on a host cell and may follow lytic or lysogenic cycles, so viral structure and reproduction differ fundamentally from those of cellular organisms such as bacteria.

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