Asked in UHS MDCAT 2017 2017Moderate

The reactions of aldehydes and ketones with ammonia derivative G-NH3 to form compounds containing >C=N-C and water is known as _ reaction.

Correct answer: D. Addition elimination

  • A. Nucleophilic addition
  • B. Nucleophilic substitution
  • C. Electrophilic addition
  • D. Addition elimination

Explanation

This reaction is called an addition-elimination reaction since a water molecule is eliminated from the reaction whereas the lone pair of electrons on Nitrogen form a dative bond with the electron-deficient carbon of aldehydes and ketones, thus adding it across the carbon.

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About Nucleophilic Addition Reactions

Nucleophilic addition occurs at the polar carbonyl group of aldehydes and ketones, where a nucleophile attacks the electron-deficient carbon atom. Reactions with hydrogen cyanide, sodium bisulfite, alcohols and Grignard reagents are explained through tetrahedral intermediates, acid or base catalysis, and the different reactivity of aldehydes and ketones.

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