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The net production of ATP in glycolysis is two molecules per glucose because

Correct answer: A. 2 ATP are invested early and 4 ATP are produced later

  • A. 2 ATP are invested early and 4 ATP are produced later
  • B. 4 ATP are invested and 2 ATP are produced
  • C. only two of glucose's six carbons can be oxidised
  • D. glycolysis occurs twice per glucose molecule

Explanation

Two ATP prime the pathway by phosphorylating glucose and its split products, and four ATP are later formed by substrate level phosphorylation, leaving a net gain of two. This investment phase is why glycolysis needs a small supply of ATP to begin with.

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About Cellular Respiration

Cellular respiration releases energy from glucose through glycolysis, the link reaction, the Krebs cycle and the electron transport chain, producing ATP. The pathway differs in oxygen availability: aerobic respiration uses oxygen and yields more ATP, while anaerobic respiration produces much less ATP and forms lactic acid in muscles or ethanol and carbon dioxide in yeast.

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