The net gain of ATP from the glycolysis of one molecule of glucose is
Correct answer: A. 2
- A. 2
- B. 4
- C. 36
- D. 38
Explanation
Four ATP are made by substrate level phosphorylation but two were invested earlier to phosphorylate glucose and fructose 6 phosphate, so the net yield is two. Four is the tempting figure because it is the gross production and is quoted in the same paragraph of most textbooks. The larger numbers belong to the complete aerobic oxidation of glucose, not to glycolysis alone.
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About Cellular Respiration
Cellular respiration releases energy from glucose through glycolysis, the link reaction, the Krebs cycle and the electron transport chain, producing ATP. The pathway differs in oxygen availability: aerobic respiration uses oxygen and yields more ATP, while anaerobic respiration produces much less ATP and forms lactic acid in muscles or ethanol and carbon dioxide in yeast.
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