Glycolysis takes place in the

  • A. matrix of the mitochondrion
  • B. inner mitochondrial membrane
  • C. cytoplasm
  • D. nucleus

Explanation

Every enzyme of glycolysis is dissolved in the cytosol, which is why the pathway runs in prokaryotes and in red blood cells that have no mitochondria at all. The later stages, the link reaction and the Krebs cycle, are the ones confined to the mitochondrial matrix, and the electron transport chain is on the inner membrane. This is also why glycolysis can continue when oxygen is absent.

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