The molecular basis of sickle cell anaemia was found by?
Correct answer: D. Ingram
- A. F. Sanger
- B. Beadle
- C. Tatum
- D. Ingram
Explanation
Ingram because Vernon Ingram discovered that sickle cell anaemia results from a single amino acid substitution (glutamic acid → valine) in the β-chain of hemoglobin, revealing the molecular basis of this genetic disease.
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Chromosomes are DNA-protein structures that carry genes and become visible during cell division. Coverage includes chromatin, centromeres, sister chromatids, homologous chromosomes, chromosome number, and the distinction between diploid and haploid cells, with links to DNA replication, mitosis and meiosis.
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