Asked in PMC Practice Test 10 (2021) 2021Moderate

The major reason behind some proteins having quaternary structure is

Correct answer: B. To assemble the monomers to form a coordinated polymeric structure.

  • A. To enable them to respond to environmental alterations
  • B. To assemble the monomers to form a coordinated polymeric structure.
  • C. In the case of enzymes, to improve their rate of catalysis.
  • D. None of the above.

Explanation

Option A: To enable them to respond to environmental alterations: Some proteins with quaternary structure can undergo conformational changes in response to changes in their environment. This allows them to adapt and perform specific functions based on the external conditions they encounter. Option B: To assemble the monomers to form a coordinated polymeric structure: This option is correct. Proteins with quaternary structure consist of multiple subunits (monomers) that come together to form a larger, functional unit. The assembly of these monomers into a coordinated polymeric structure enhances the protein's stability, functionality, and overall efficiency. Option C: In the case of enzymes, to improve their rate of catalysis: While quaternary structure can enhance enzyme catalysis, it is not the primary reason for the formation of quaternary structure in proteins. Option D: None of the above: This option is not correct

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Proteins are polymers of amino acids joined by peptide bonds, and their function depends on primary, secondary, tertiary and quaternary structure. The topic covers fibrous and globular proteins, enzymes, antibodies, hormones and transport proteins, as well as denaturation by heat or extreme pH.

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