The major factor in producing hypertonic urine is:

Correct answer: D. Gradual increase in osmolarity from cortex to medullary portion.

  • A. Glomerulus.
  • B. Influence of aldosterone.
  • C. ADH influencing on collecting duct.
  • D. Gradual increase in osmolarity from cortex to medullary portion.

Explanation

The major factor in producing hypertonic urine in mammals is gradually increasing osmotic concentration from the cortex to the medulla. Juxtamedullary nephrons are specifically instrumental in the production of concentrated urine via a counter current mechanism which uses high medullary osmolarity.

This question appeared on the UHS MDCAT 2017 paper, which you can sit online with every answer explained.

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About Kidney and Urinary System

The kidney and urinary system remove nitrogenous wastes, regulate water and ion balance, and help maintain blood pH through filtration, selective reabsorption and secretion. Questions cover nephron structure, ultrafiltration, the loop of Henle, collecting ducts, urine formation and the roles of ADH and aldosterone, while distinguishing excretion from egestion.

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