The lock and key model was proposed by?
Correct answer: A. Emil Fischer
- A. Emil Fischer
- B. Koshland
- C. Watson and Crick
- D. Rosalind Franklin
Explanation
The correct answer is Emil Fischer, who proposed the lock and key model, which describes how enzymes are specifically shaped to fit substrates, like a key fitting into a lock. This model emphasizes the specificity of enzyme-substrate interactions.Option Koshland is incorrect as he developed the induced fit model, which differs from the lock and key concept by suggesting that the enzyme's structure can change upon substrate binding, allowing for a more flexible interaction.Options Watson and Crick and Rosalind Franklin are also incorrect, as their contributions were primarily focused on the structure of DNA, with no direct relation to enzyme action models.
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About Enzymes
Enzymes are biological catalysts that lower activation energy without being consumed, and their specificity is explained by the lock and key and induced fit models. Work includes the effects of temperature, pH and substrate concentration on reaction rate, plus competitive and non-competitive inhibition and how these differ.
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