The histopathology of osteopetrosis shows_______________?
Correct answer: A. Endosteal bone formation and lack of normal bone resorption
- A. Endosteal bone formation and lack of normal bone resorption
- B. Periosteal bone formation and lack of normal bone resorption
- C. Persence of extra collagen fibres and less calcification resulting in resistance of bones to fracture
- D. Presence of numerous osteoclasts and a few osteoblasts
Explanation
Osteopetrosis results from failure of osteoclastic bone resorption, with excessive endosteal bone formation and progressive obliteration of marrow spaces. Extra collagen with poor mineralization describes osteogenesis imperfecta more closely.
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