Asked in Premeth past paper pool — BiologyModerate

The given graph shows the effect of substrate concentration, with and without inhibitor, on the rate of enzyme-catalysed reaction.The inhibitor X is identified as:

Correct answer: A. Reversible and Competitive inhibitor

  • A. Reversible and Competitive inhibitor
  • B. Irreversible and Competitive inhibitor
  • C. Reversible and Non-competitive inhibitor
  • D. Irreversible and Non-competitive inhibitor

Explanation

Inhibitors that do not change Vmax are typically competitive inhibitors. Non-competitive inhibitors always lower the apparent Vmax. So option C and D are wrong because graph have same Vmax with or without inhibitor.Increasing the concentration of substrate increases the chances of substrate to bind with the active site, if irreversible inhibitor is present it will attach permanently reducing the Vmax. So option A is correct.

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About Enzyme Inhibitors

Enzyme inhibitors reduce reaction rate by interfering with enzyme-substrate interaction or catalytic activity. Coverage includes reversible competitive, non-competitive and uncompetitive inhibition, the effects of inhibitor concentration on reaction rate, and why competitive inhibition can be reduced by increasing substrate concentration.

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