Asked in Premeth past paper pool — BiologyModerate

Consider the given metabolic reactions I and II.In the metabolic reaction II, product is NOT formed because malonate acts as a/an

Correct answer: C. competitive inhibitor

  • A. allosteric inhibitor
  • B. irreversible inhibitor
  • C. competitive inhibitor
  • D. non-competitive inhibitor

Explanation

Malonate is a competitive inhibitor, which means it competes with the substrate for the active site of the enzyme. In the context of metabolic reactions, when malonate is present, it binds to the active site of the enzyme instead of the substrate, preventing the formation of the product. This is why in metabolic reaction II, the product is NOT formed. Competitive inhibition can be overcome by increasing the concentration of the substrate.Allosteric inhibitors, on the other hand, bind to a site other than the active site, inducing a conformational change that reduces enzyme activity. Irreversible inhibitors form covalent bonds with enzymes, leading to permanent inhibition, while non-competitive inhibitors reduce enzyme activity by binding elsewhere and are not affected by substrate concentration.

Last updated

About Enzyme Inhibitors

Enzyme inhibitors reduce reaction rate by interfering with enzyme-substrate interaction or catalytic activity. Coverage includes reversible competitive, non-competitive and uncompetitive inhibition, the effects of inhibitor concentration on reaction rate, and why competitive inhibition can be reduced by increasing substrate concentration.

Practise Enzymes

633 free Enzymes MCQs from Biology, each with the correct answer and an explanation. Unlimited attempts, no account needed.

Exams that ask Biology questions like this

Biology is on 6 papers prepared for on TestUstad, and all of them draw the same bank, so this question is worth knowing for every one of them.

Related questions