The functional group of an amide is
Correct answer: A. CONH2, in which nitrogen is bonded directly to the carbonyl carbon
- A. CONH2, in which nitrogen is bonded directly to the carbonyl carbon
- B. COOH
- C. COOR
- D. COCl
Explanation
In an amide the nitrogen lone pair is delocalised into the carbonyl group, which is why amides are almost neutral rather than basic like amines, and why they are the least reactive of the acid derivatives. The peptide link joining amino acids in a protein is exactly this group. COOR is the ester group and COCl the acyl chloride.
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About Carboxylic Acid Derivatives
Carboxylic acid derivatives include acid halides, acid anhydrides, esters and amides, formed by replacing the hydroxyl group of a carboxylic acid. Their nomenclature, structures, preparation, hydrolysis and relative reactivity are linked through nucleophilic acyl substitution, which differs from the nucleophilic addition reactions of aldehydes and ketones.
Practise Carboxylic Acids
550 free Carboxylic Acids MCQs from Chemistry, each with the correct answer and an explanation. Unlimited attempts, no account needed.
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