The functional group of an amide is

  • A. CONH2, in which nitrogen is bonded directly to the carbonyl carbon
  • B. COOH
  • C. COOR
  • D. COCl

Explanation

In an amide the nitrogen lone pair is delocalised into the carbonyl group, which is why amides are almost neutral rather than basic like amines, and why they are the least reactive of the acid derivatives. The peptide link joining amino acids in a protein is exactly this group. COOR is the ester group and COCl the acyl chloride.

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