The following immunoglobulin is not known to fix complement_________________?

Correct answer: A. IgE

  • A. IgE
  • B. IgM
  • C. IgA
  • D. IgG

Explanation

IgE does not normally activate the complement system, unlike IgM and most IgG, which are important classical-pathway antibodies. IgA is also a weak complement activator, especially in secretions, but IgE is the standard answer.

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