The first step of glycolysis is the transfer of a phosphate group from:

Correct answer: A. ATP to glucose

  • A. ATP to glucose
  • B. G3P to ATP
  • C. ATP to fructose
  • D. ATP to G3P

Explanation

The correct answer is that the first step of glycolysis involves the transfer of a phosphate group from ATP to glucose, forming glucose 6-phosphate. This step is catalyzed by the enzyme hexokinase and is essential for trapping glucose within the cell and making it more reactive for further metabolism. Option B (G3P to ATP) is incorrect because G3P is involved in generating ATP in later steps, not in the initial phosphorylation. Option C (ATP to fructose) is incorrect, as fructose phosphorylation occurs later in glycolysis. Option D (ATP to G3P) is incorrect because G3P is a later intermediate in the glycolytic pathway, not part of the first step.

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