The first human hormone that was produced by recombinant DNA technology was:
Correct answer: A. Insulin
- A. Insulin
- B. Estrogen
- C. Thyroxin
- D. Progesterone
Explanation
The recombinant DNA technological processes have made a great impact in the area of health care by mass production of safe and more effective therapeutic drugs. In 1983, Eli Lily, an American company, first prepared two DNA sequences corresponding to A and B chains of human insulin and introduced them in plasmids of Escherichia coli to produce insulin chains. Chains A and B were produced separately, extracted, and combined by creating disulfide bonds to form human insulin (humulin).
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About Biotechnology
Biotechnology in health care applies biological organisms, cells or enzymes to diagnose and treat disease. The subject includes recombinant DNA, genetically engineered insulin, vaccines, antibiotics, monoclonal antibodies, gene therapy and techniques such as polymerase chain reaction, while distinguishing therapeutic applications from agricultural and industrial biotechnology.
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