The correct reactivity order of the following compounds towards nucleophile is
Correct answer: C. H-CO-H > H-CO-R > R-CO-R
- A. H-СО-Н <H-CO-R < R-CO-R
- B. H-CO-R< H-CO-R ≥ R-CO-R
- C. H-CO-H > H-CO-R > R-CO-R
- D. H-CO-H> R-CO-R> H-CO-R
Explanation
Formaldehyde is the most reactive towards nucleophiles due to high electrophilicity and low steric hindrance. Ketones are the least reactive due to lower electrophilicity and higher steric hindrance.
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About Aldehydes and Ketones
Aldehydes and ketones contain the polar carbonyl group, but aldehydes are generally more readily oxidised and more reactive than ketones. Coverage includes preparation by oxidation or reduction routes, nucleophilic addition of reagents such as hydrogen cyanide and bisulfite, and tests that distinguish aldehydes from ketones.
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