The centromere is a region in which:
Correct answer: A. Chromatids remain attached to one another until anaphase
- A. Chromatids remain attached to one another until anaphase
- B. Metaphase chromosomes become aligned at the metaphase plate
- C. Chromosomes are grouped during telophase
- D. The nucleus is located prior to mitosis
Explanation
The centromere is a specialized region of a chromosome where two sister chromatids are held together until they separate during anaphase of cell division. During metaphase of mitosis or meiosis II, the sister chromatids are aligned at the metaphase plate, and the centromere acts as a point of attachment for microtubules from the spindle apparatus. These microtubules exert tension on the sister chromatids, ensuring that they are properly aligned. During anaphase, the proteins that hold the sister chromatids together at the centromere are degraded, allowing the sister chromatids to separate and move towards opposite poles of the cell. This ensures that each daughter cell receives the correct number of chromosomes.
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