Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement:

Explanation

Sickle cell anemia is caused due to point mutation in which at the 6th position of the beta-globin chain, glutamic acid is replaced by valine. Thus, it is a qualitative defect in the functioning of globin molecules. Sickle cell anemia is caused due to point mutation in which at the 6th position of the beta-globin chain, glutamic acid is replaced by valine. Thus, it is a qualitative defect in the functioning of globin molecules. Thalassemia is caused due to either mutation or deletion which ultimately results in a reduced rate of synthesis of one of the globin chains that make up hemoglobin. Hence, it is a quantitative defect in the functioning of globin molecules.ing of globin molecules.