Sildenafil is inhibitor of_______________?

Correct answer: C. PDE-5

  • A. cAMP
  • B. cGMP
  • C. PDE-5
  • D. PGI2

Explanation

Sildenafil selectively inhibits phosphodiesterase-5, preventing cGMP breakdown and thereby prolonging smooth-muscle relaxation. It does not inhibit cGMP itself; rather, it increases cGMP levels.

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