Asked in ETEA MDCAT 2015 2015Moderate

Phosphodiester linkage is formed between.

Correct answer: D. Nucleotides and phosphates

  • A. Two nucleotide bases
  • B. Amino acid
  • C. Two sugar
  • D. Nucleotides and phosphates

Explanation

In the polynucleotide, adjacent nucleotides are joined by a phosphodiester linkage, which consists of a phosphate group that links the sugars of two nucleotides. This bonding results in a repeating pattern of sugar-phosphate units called the sugar-phosphate backbone. (Note that the nitrogenous bases are not part of the backbone.) Complementary nitrogenous bases are held together by hydrogen bonds.

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About Structure of DNA

DNA structure includes nucleotides made of deoxyribose, phosphate and nitrogenous bases, arranged in two antiparallel polynucleotide strands. Questions cover the double helix, phosphodiester and hydrogen bonds, complementary base pairing between adenine and thymine and between guanine and cytosine, and the significance of major and minor grooves.

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