Asked in PMC Practice Test 27 (2021) 2021

Phopho-glyceromutases are example of:

Correct answer: A. Lyases

  • A. Lyases
  • B. Hydrolases
  • C. Ligases
  • D. Transferases

Explanation

Option A is correct since lyases are enzymes that catalyze the breakdown of specific covalent bonds and the removal of groups without hydrolysis. Since phosphoglyceromutase catalyzes the following reaction:It is classified as a lyase.Option B is incorrect since hydrolases are enzymes that bring about the breakdown of large complex organic molecules into smaller ones by adding water (hydrolysis) and breaking the specific covalent bonds.Option C is incorrect since ligases are enzymes that bring about the joining together of two molecules.Option D is incorrect since transferases catalyze the transfer of a specific functional group other than hydrogen from one substrate to another. The chemical group transferred in the process is not in a free state.

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About Enzymes as Biocatalysts

Enzymes are protein or RNA biocatalysts that lower activation energy without being consumed, and their active sites bind specific substrates. The topic covers the lock and key and induced fit models, effects of temperature, pH and substrate concentration, cofactors, enzyme specificity, and competitive versus non-competitive inhibition.

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