One molecule of FADH2 is produced in Krebs cycle during conversion of:
Correct answer: B. Succinate to fumarate
- A. Fumarate to malate
- B. Succinate to fumarate
- C. Malate to oxaloacetate
- D. Alpha Ketoglutarate to succinate
Explanation
Only one molecule of FADH2 is produced in the Krebs cycle during the conversion of succinate to fumarate.FADH2 is a reduced form of flavin adenine dinucleotide (FAD). It is produced when FAD is oxidized by the enzyme succinate dehydrogenase. Succinate dehydrogenase is a membrane-bound enzyme that is located in the inner mitochondrial membrane.The oxidation of succinate to fumarate by succinate dehydrogenase releases two electrons. These electrons are then transferred to FAD, which is reduced to FADH2.FADH2 can then enter the electron transport chain and be used to produce ATP. However, it produces fewer ATP molecules than NADH. For every molecule of FADH2 that is oxidized, only 2 protons are pumped across the inner mitochondrial membrane. This creates enough energy to synthesize 2 ATP molecules.
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About Bioenergetics
Cellular respiration explains how cells release energy from glucose through glycolysis, the link reaction, Krebs cycle and electron transport chain. It includes ATP production, substrate-level and oxidative phosphorylation, aerobic versus anaerobic respiration, and the roles of mitochondria, oxygen and fermentation in energy transfer.
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