Moderate

Okazaki fragments are formed in lagging strand because:

Correct answer: B. Lagging strand is 3 to 5 direction

  • A. Lagging strand does not allow continuous replication
  • B. Lagging strand is 3 to 5 direction
  • C. Lagging strand is 5 to 3 direction
  • D. Lagging strand is placed near to leading strand

Explanation

The main reason for Okazaki fragments forming on the lagging strand is the antiparallel nature of DNA strands and the requirement for DNA polymerase to synthesize DNA in the 5' to 3' direction. Because the DNA polymerase can only add nucleotides in the 5' to 3' direction, the lagging strand, which runs in the opposite direction from the replication fork, has to be synthesized discontinuously in short fragments, each of which starts with an RNA primer. These fragments are then later joined together by DNA ligase to form a continuous strand.

Last updated

About Chromosomes

Chromosomes are DNA-protein structures that carry genes and become visible during cell division. Coverage includes chromatin, centromeres, sister chromatids, homologous chromosomes, chromosome number, and the distinction between diploid and haploid cells, with links to DNA replication, mitosis and meiosis.

Practise Cell Structure and Function

2,478 free Cell Structure and Function MCQs from Biology, each with the correct answer and an explanation. Unlimited attempts, no account needed.

Exams that ask Biology questions like this

Biology is on 6 papers prepared for on TestUstad, and all of them draw the same bank, so this question is worth knowing for every one of them.

Related questions