Negri bodies in a suspected case of rabies are classically found in the:
Correct answer: B. Neurons of the central nervous system
- A. Hepatocytes and Kupffer cells
- B. Neurons of the central nervous system
- C. Renal tubular epithelium
- D. Skeletal muscle fibres
Explanation
Negri bodies are eosinophilic intracytoplasmic inclusion bodies found in neurons during rabies infection, especially in the hippocampus and cerebellar Purkinje cells. The other listed tissues are not the characteristic sites of these inclusions.
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Covers the causes and mechanisms of disease, cellular injury, inflammation, healing, circulatory disturbances, neoplasia and disorders of major organs. It also includes gross and microscopic pathological changes, specimen interpretation and the distinction between aetiology, pathogenesis, clinical signs and lesions.
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