Metaplasia is best defined as which type of cellular adaptation?
Correct answer: B. Reversible replacement by another mature cell type
- A. Irreversible transformation into a malignant cell
- B. Reversible replacement by another mature cell type
- C. Increase in cell size without tissue replacement
- D. Increase in cell number after permanent injury
Explanation
Metaplasia is a reversible change in which one differentiated adult cell type is replaced by another better suited to persistent stress. It is not itself malignant transformation, although prolonged irritation may increase neoplastic risk.
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Covers the causes and mechanisms of disease, cellular injury, inflammation, healing, circulatory disturbances, neoplasia and disorders of major organs. It also includes gross and microscopic pathological changes, specimen interpretation and the distinction between aetiology, pathogenesis, clinical signs and lesions.
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