Mechanism of action of nifidipine is_____________?

Correct answer: A. It has a prominent smooth muscle relaxant action causes arteolar dilation leading to fall in blood pressure

  • A. It has a prominent smooth muscle relaxant action causes arteolar dilation leading to fall in blood pressure
  • B. Nifidipine depresses the SA node thus decreasing mycocoardial excitability
  • C. Mainly depression of A-V conduction
  • D. Decreased cardiac output thus decreasing load on myocardium

Explanation

Nifedipine blocks L-type calcium channels predominantly in vascular smooth muscle, causing arteriolar dilation and a fall in systemic blood pressure. Unlike verapamil, it does not primarily depress the SA node or AV conduction.

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