L - Asparaginase enzyme has been used for the treatment of:
Correct answer: B. Blood cancer
- A. Jaundice
- B. Blood cancer
- C. Rickets
- D. Heart disease
Explanation
L-asparaginase is an enzyme that has been used in the treatment of certain types of cancer, particularly acute lymphoblastic leukemia. L-asparaginase works by depleting levels of the amino acid asparagine in the blood. Cancer cells, unlike normal cells, are unable to synthesize their own asparagine and rely on external sources. By depleting asparagine, L-asparaginase interferes with the growth and survival of cancer cells, ultimately leading to their death.
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About Enzymes
Enzymes are biological catalysts that lower activation energy without being consumed, and their specificity is explained by the lock and key and induced fit models. Work includes the effects of temperature, pH and substrate concentration on reaction rate, plus competitive and non-competitive inhibition and how these differ.
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