Moderate

Iron is complexed in haemoglobin to_______________?

Correct answer: B. Histidine

  • A. Leucine
  • B. Histidine
  • C. Isoleucine
  • D. Valine

Explanation

Haem iron is coordinated to a proximal histidine residue of the globin chain, in addition to its four bonds with the porphyrin nitrogens. The distal histidine helps bind and orient oxygen but does not directly coordinate the iron.

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