At PH 7 the binding of 2,3 DPG to hemoglobin occurs at which site ?

Correct answer: C. Amino terminal

  • A. Sulphydryl group
  • B. Carboxy terminal
  • C. Amino terminal
  • D. Histidine

Explanation

At physiological pH, 2,3-DPG binds in the positively charged central cavity between haemoglobin's beta chains, interacting mainly with amino-terminal residues. This stabilises deoxyhaemoglobin and promotes oxygen release.

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