Increasing the substrate concentration will NOT relieve the effect of
Correct answer: B. a non-competitive inhibitor
- A. a competitive inhibitor
- B. a non-competitive inhibitor
- C. a low enzyme concentration
- D. a substrate below the saturation point
Explanation
A non-competitive inhibitor binds at a site other than the active site and changes the enzyme's shape, so the substrate cannot compete it away no matter how much is added and Vmax is genuinely reduced. Competitive inhibition, by contrast, is overcome by flooding the system with substrate. This difference is the standard way of telling the two apart experimentally.
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About Enzyme Inhibitors
Enzyme inhibitors reduce reaction rate by interfering with enzyme-substrate interaction or catalytic activity. Coverage includes reversible competitive, non-competitive and uncompetitive inhibition, the effects of inhibitor concentration on reaction rate, and why competitive inhibition can be reduced by increasing substrate concentration.
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