Increased levels of haemoglobin A2 is characteristic of________________?

Correct answer: B. b-thalassaemia crait

  • A. Sickle cell trait
  • B. b-thalassaemia crait
  • C. Glucose-6 phosphate dehydrogenase deficiency
  • D. a-Thalassamia

Explanation

Beta-thalassemia trait increases delta-chain pairing because beta-chain production is reduced, leading to increased HbA2. This rise in HbA2 is a useful discriminator from alpha-thalassemia and sickle-cell trait.

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