A 3-year old child presented with progressive anaemia, jaundice & failure to thrive. O/E: pallor, splenomegaly are seen Peripheral smear showed normoblasts and small round intensely stained red cells. The likely diagnosis is________________?
Correct answer: A. Here ditary spherocytosis
- A. Here ditary spherocytosis
- B. Thalassaemia
- C. Sickle cell anaemia
- D. Vitamin B12 deficiency anaemia
Explanation
Hereditary spherocytosis causes spherical, densely staining red cells due to a red-cell membrane defect, with extravascular hemolysis causing anemia, jaundice and splenomegaly. Thalassemia more typically shows marked microcytosis and target cells.
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