Increase in lactate and pyruvate is seen in deficiency of_____________?
Correct answer: C. Thiamine
- A. Pyridoxin
- B. Niacin
- C. Thiamine
- D. Retinotic acid
Explanation
Thiamine pyrophosphate is required by pyruvate dehydrogenase, so its deficiency blocks pyruvate oxidation and causes accumulation of pyruvate and lactate. Niacin deficiency affects NAD-dependent reactions but does not produce this characteristic block.
Last updated
Practise Metabolism and Bioenergetics
68 free Metabolism and Bioenergetics MCQs from Biochemistry, each with the correct answer and an explanation. Unlimited attempts, no account needed.
Exams that ask Biochemistry questions like this
Biochemistry is on 3 papers prepared for on TestUstad, and all of them draw the same bank, so this question is worth knowing for every one of them.
Related questions
A relatively component of the electron transporting respiratory chain is_____________?
Acetyl Co-A acts as a substrate for all the enzymes except______________?
Acetyl CoA is produced from which fuel sources_____________?
Adrenaline acts on which enzyme in glycogenolysis ?
Alkaptonuria an inherited metabolic disorder is due to the deficiency of____________?