In translation, methionine is released from its tRNA and is attached instead by a peptide bond to the second amino acid. This is catalyzed by:

Correct answer: D. Large ribosomal subunit

  • A. Small ribosomal subunit
  • B. Initiation factor
  • C. Elongation factor
  • D. Large ribosomal subunit

Explanation

The two amino acids which lie adjacent to each other undergo a chemical reaction, catalyzed by the large ribosomal subunit, which releases the initial amino acid from its tRNA and attaches it instead by a peptide bond to the second amino acid. The large ribosomal subunit plays a crucial role in the formation of peptide bonds during the elongation phase of translation, which is catalyzed by the ribozyme activity of the ribosomal RNA (rRNA) components in the large subunit.

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