Moderate

In the DNA replication diagram, the enzyme joining Okazaki fragments is:

Correct answer: B. Ligase

  • A. DNA polymerase I
  • B. Ligase
  • C. Primase
  • D. Topoisomerase

Explanation

During lagging strand synthesis, short DNA segments (Okazaki fragments) are produced. DNA polymerase fills the gaps but leaves nicks between fragments. DNA ligase seals these nicks by forming phosphodiester bonds, joining fragments into one continuous strand.

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Chromosomes are DNA-protein structures that carry genes and become visible during cell division. Coverage includes chromatin, centromeres, sister chromatids, homologous chromosomes, chromosome number, and the distinction between diploid and haploid cells, with links to DNA replication, mitosis and meiosis.

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