In sickle cell hemoglobin only one glutamic acid of normal hemoglobin is replaced by?
Correct answer: A. Valine acid
- A. Valine acid
- B. Alamine acid
- C. Arginine acid
- D. Methionine acid
Explanation
Sickle cell anemia results from the single amino acid substitution of valine for glutamic acid in the beta-chain owing to a nucleotide defect that causes the production of abnormal beta-chains in hemoglobin S. (Hemoglobin S, a variant form of hemoglobin, is present in patients with sickle cell disease ).
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