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In order to construct another Okazaki fragment, DNA polymerase III jumps:

Correct answer: C. Away from replication fork

  • A. Towards replication fork
  • B. Towards another DNA molecule
  • C. Away from replication fork
  • D. Towards other strand of DNA molecule

Explanation

Overall, the process of replication is always towards the replication fork. DNA polymerase III can add nucleotides only at 3 ends of the primer, and to construct the okazaki fragment, DNA polymerase IIl jumps away from the replication fork. In order to construct another Okazaki fragment on the lagging strand, DNA polymerase III jumps away from the replication fork. DNA polymerase III cannot synthesise DNA in the 5' to 3' direction continuously on the lagging strand, as it can on the leading strand. Instead, it synthesises short segments of DNA in the 5' to 3' direction, away from the replication fork.

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